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郝晨路, 於晓芬, 曲明昊, 赖恩惠, 郭素敏, 高磊. 植物泛基因组研究进展与展望[J]. 植物科学学报, 2022, 40(1): 124-132. DOI: 10.11913/PSJ.2095-0837.2022.10124
引用本文: 郝晨路, 於晓芬, 曲明昊, 赖恩惠, 郭素敏, 高磊. 植物泛基因组研究进展与展望[J]. 植物科学学报, 2022, 40(1): 124-132. DOI: 10.11913/PSJ.2095-0837.2022.10124
Hao Chen-Lu, Yu Xiao-Fen, Qu Ming-Hao, Lai En-Hui, Guo Su-Min, Gao Lei. Current status and prospects of pan-genome studies in plants[J]. Plant Science Journal, 2022, 40(1): 124-132. DOI: 10.11913/PSJ.2095-0837.2022.10124
Citation: Hao Chen-Lu, Yu Xiao-Fen, Qu Ming-Hao, Lai En-Hui, Guo Su-Min, Gao Lei. Current status and prospects of pan-genome studies in plants[J]. Plant Science Journal, 2022, 40(1): 124-132. DOI: 10.11913/PSJ.2095-0837.2022.10124

植物泛基因组研究进展与展望

Current status and prospects of pan-genome studies in plants

  • 摘要: 随着测序技术和生物信息学的快速发展,已有数百种植物的参考基因组被测序,极大地促进了植物功能基因组学、进化遗传学和分子育种学等领域的蓬勃发展。然而,随着研究的深入,越来越多的证据表明来自单一个体的参考基因组远不能代表整个物种的遗传多样性,由此催生了泛基因组(Pan-genome)的概念,并已成功应用于20余种植物的研究,揭示了丰富的遗传变异,发掘了大量的新基因,深化了对相关物种遗传多样性的认识。本文简述了泛基因组的概念、构建方法以及在当前植物研究中的应用现状,最后对其未来发展进行了展望。

     

    Abstract: With the rapid development of sequencing technology and bioinformatics, hundreds of plant reference genomes have been sequenced, which has greatly promoted the development of plant functional genomics, evolutionary genetics, and molecular breeding. However, increasing evidence suggests that one reference from a single individual is insufficient to comprehensively understand the genetic diversity of a given species. The pan-genome concept has been proposed and successfully employed in studies of more than 20 plant species, uncovering abundant novel genes and genetic variations and deepening our understanding of genetic diversity. Here, we briefly introduce the concept and construction of pan-genomes, as well as their applications, development, and prospects in plant research.

     

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